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- Studies of Neurofibromatosis clinical trials
Neurofibromatosis Clinical Trials - Mayo Clinic Research
WEBBrowse Clinical Trials. neurofibromatosis. Displaying 5 studies. The Collection of Blood Samples from Patients With NF1 for Research Purposes Rochester, MN. The objective of this study is to collect blood samples from living patients with neurofibromatosis type 1 …
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Neurofibromatosis Clinical Trials - Johns Hopkins Medicine
WEBThe neurofibromatosis team at Hopkins is building a clinical database that can predict which NF patients are most at risk for specific tumor types. With this improved accuracy, …
Selumetinib in Children with Inoperable Plexiform …
WEBMar 18, 2020 · In a phase 1 trial of the oral selective MEK inhibitor selumetinib (AZD6244 or ARRY-142886) involving 24 children with …
- Author: Andrea M. Gross, Pamela L. Wolters, Eva Dombi, Andrea Baldwin, Patricia Whitcomb, Michael J. Fisher,...
- Publish Year: 2020
FDA Approves First Ever Treatment for Neurofibromatosis
WEBApr 10, 2020 · The U.S. Food and Drug Administration (FDA) has approved Koselugo (selumetinib) for use in patients with inoperable plexiform neurofibromas, a common …
A Systematic Review of Recent and Ongoing Clinical …
WEBJun 10, 2022 · This review summarizes recent and ongoing clinical trials involving patients with neurofibromatoses to better understand the current state of clinical trial research centered around these conditions and …
Clinical Trials for Neurofibromatosis | NYU Langone Health
WEBAs the only participating neurofibromatosis center in the New York tri-state region, we are pleased to offer such important and promising new treatments for people with …
Neurofibromatosis Clinical Trials—REiNS Collaboration 2020 ...
WEBAug 17, 2021 · Neurofibromatosis (NF) type 1 (NF1), NF type 2 (NF2), and schwannomatosis are genetic tumor predisposition syndromes with a wide variety of …
Clinical Trials for Neurofibromatosis | Moffitt | Moffitt
WEBClinical trials offer unique treatment opportunities for patients with neurofibromatosis. Learn about these important medical research studies here.
Brigatinib in NF2-Related Schwannomatosis with Progressive …
WEBJun 20, 2024 · NF2 -related schwannomatosis ( NF2 -SWN, formerly called neurofibromatosis type 2) is a tumor predisposition syndrome that is manifested by …
NF106: A Neurofibromatosis Clinical Trials …
WEBJan 28, 2021 · Purpose. Patients with neurofibromatosis type 1 (NF1) frequently develop plexiform neurofibromas (PNs), which can cause significant morbidity. We performed a phase II trial of the MAPK/ERK …
Clinical Trials | Neurofibromatosis Center | Washington University …
WEBOur clinical trials aim to determine how drugs and other therapies can prevent or treat medical problems seen in individuals with NF1 and NF2. Search for additional current …
NF106: A Neurofibromatosis Clinical Trials Consortium Phase II …
WEBMar 1, 2021 · Abstract. Purpose: Patients with neurofibromatosis type 1 (NF1) frequently develop plexiform neurofibromas (PNs), which can cause significant morbidity. We …
NF Clinical Trials Consortium - Neurofibromatosis Program
WEBNew medications currently being tested in clinical trials block altered cell signaling pathways, providing a potential means of shrinking existing neurofibromas or preventing …
A Systematic Review of Recent and Ongoing Clinical Trials in
WEBThis review summarizes recent and ongoing clinical trials involving patients with neurofibromatoses to better understand the current state of clinical trial research …
University of California Health Neurofibromatosis Clinical Trials ...
WEBMay 23, 2024 · MEK Inhibitor Mirdametinib (PD-0325901) in Patients With Neurofibromatosis Type 1 Associated Plexiform Neurofibromas. This study evaluates …
Neurofibromatosis Clinic - Overview - Mayo Clinic
WEBJun 12, 2024 · We provide clinical evaluations for neurofibromatosis (type 1 and type 2) and schwannomatosis — and all of our physicians have significant experience treating …
Activity of Selumetinib in Neurofibromatosis Type 1–Related …
WEBDec 29, 2016 · We conducted a phase 1 trial of selumetinib (AZD6244 or ARRY-142886), an oral selective inhibitor of MAPK kinase (MEK) 1 and 2, in children who had …
Neurofibromatosis Research Program, Clinical Trials Consortium ...
WEBMay 26, 2022 · The Neurofibromatosis Clinical Trials Consortium (NFCTC, http://www.uab.edu/nfconsortium) was established by the Department of Defense …
Clinical Trials - Neurofibromatosis Program - The University of …
WEBClinical trials are essential for testing the effectiveness of promising new therapies to improve the lives of people with neurofibromatosis. Many people living with NF are …
Neurofibromatosis - National Institute of Neurological Disorders …
WEBNov 28, 2023 · Clinical trials. NINDS supports clinical trials aimed at understanding tumor growth and cognitive impairments in children, including: Studying the natural history of …
Clinical Drug Pipeline - Children's Tumor Foundation
WEBThe Neurofibromatosis Clinical Trials Consortium (NFCTC) was established by the Department of Defense Neurofibromatosis Research Program (NFRP) to develop and …
Neurofibromatosis clinical trials - University of Florida
WEBTo learn more see https://www.ctsi.ufl.edu/. Please contact Hans Shuhaiber at [email protected] and/or ( 312) 286 1059 for information about these …
Emerging therapeutic targets for neurofibromatosis type 1 (NF1)
WEBNeurofibromatosis type 1 (NF1) is an autosomal dominantly inherited tumor predisposition syndrome with an incidence of one in 3000–4000 individuals with no currently effective …
Genotype-phenotype correlations and treatment innovation of ...
WEBJun 25, 2024 · NF106: A Neurofibromatosis Clinical Trials Consortium Phase II Trial of the MEK Inhibitor Mirdametinib (PD-0325901) in Adolescents and Adults With NF1-Related …
Diagnostics | Free Full-Text | Neurofibromatosis Type 1&mdash …
WEB1 day ago · Neurofibromatosis type 1 (NF 1) is a multisystemic genetic disorder involving aberrant proliferation of multiple tissues of a neural crest origin. It represents a tumor …
Painful Swelling in a Case of Neurofibromatosis 1: An... : Indian ...
WEBIndian Dermatology Online Journal 15 (4):p 646-648, Jul–Aug 2024. | DOI: 10.4103/idoj.idoj_145_23. Open. Metrics. Dear Editor, Neurofibromatosis 1 (NF1) is an …
Early change of plasma Epstein-Barr virus DNA load and the viral …
WEB3 days ago · Patients with recurrent or metastatic nasopharyngeal carcinoma (RM-NPC) have proven benefit from anti-programmed cell death 1 (anti-PD-1) monotherapy. Here, …
Trial: Fenofibrate Slows Diabetic Retinopathy Progression
WEBJun 23, 2024 · The 16-center trial was embedded into routine clinical care at 11 National Health Service centers in Scotland, from September 2018 through July 2021. A total of …
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